If you've been on skincare TikTok lately, you've seen "salmon DNA" everywhere. It sounds intense, but it's one of the most loved hydrating ingredients in Korean skincare. Here's the plain-English version.
What is PDRN?
PDRN stands for polydeoxyribonucleotide — a fragment derived (yes) from salmon DNA, chosen because it's remarkably similar to human DNA and very well tolerated by skin. In cosmetics, it's prized as a deeply hydrating, soothing ingredient that helps skin look plump, bouncy, and refreshed.
What people love it for
- A dewy, "just-left-the-facial" glow — it floods skin with moisture.
- Plump, bouncy-looking skin — great for dullness and tired skin.
- Comfort — it's gentle, making it a favorite for post-treatment care.
(To be clear: these are cosmetic, appearance-level benefits — PDRN skincare hydrates and improves how skin looks and feels.)
How to use it
Salmon-DNA products come as sheet masks, leave-on boosters or serums, and creams:
- Mask: 2-3 times a week for an instant moisture hit. (Our Salmon DNA mask is a bestseller.)
- Daily booster: pat onto damp skin after cleansing, before moisturizer.
- Cream: as your final PM step to seal it all in.
Who is it for?
Pretty much every skin type — especially dry, dull, or tired skin, and anyone chasing the glass-skin look. As always, patch-test first if you're sensitive.
Try it
Explore our authentic salmon-DNA range — sealed, genuine, and shipped from LA in 1-2 days. New here? Browse the Hydrating edit or the full range.